InvivoGen’s Lucia™ is a completely novel and optimized luciferase with strong bioluminescent activity. It is expressed by a synthetic gene designed on natural secreted luciferase genes from marine copepods.
Lucia™ is a secreted coelenterazine-utilizing luciferase that generates 1000-fold higher bioluminescent signal compared to the commonly used Firefly and Renilla luciferases. Lucia™ is designed for high and prolonged expression in mammalian cells.
Lucia™ has several advantages over currently available luciferases and reporter systems, which are highlighted below:
- Lucia is efficiently secreted into the cell culture supernatant.
- Reporter activity is determined fast and easily in real-time without disturbing cells in one simple endpoint assay.
- Stable expression of Lucia™ makes this reporter system ideal for use in cell based assays and high-throughput applications.