GenePix 4300A & 4400A Microarray Scanners from Molecular Devices LLC

Product Specs
ItemGenePix 4300A & 4400A Microarray Scanners
CompanyMolecular Devices LLC
Price Get Pricing Get Quote for this Product
Catalog NumberGenePix 4300A / GenePix 4300A
Sample TypeStandard microscope slides
Electrical Requirements85 to 264 VAC (110 to 340 VDC) universal voltage input
DetectorPhotomultiplier tube (PMT) automatic and manual gain adjustment settings
Resolution4300A-Adjustable from 5-100 µm / 4400A-Adjustable from 2.5-100 µm
Wavelength(s)488 nm / 532 nm / 594 nm / 635 nm
Optical SystemNon-confocal
LasersUp to 4 lasers (all internal); 488 nm, 532 nm, 594 nm, 635 nm
Scan Area22 x 72 mm (Max)

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Molecular Devices LLC

3860 N First Street

San Jose, California 95134

United States

Phone: 408-747-1700

Company Profile

Website: http://www.moleculardevices.com/

(1) Sterile protection against P. vivax malaria by repeated blood stage infection in the Aotus monkey modelLife Sci AllianceDecember 29, 2023Nicanor Obaldía, Joao Luiz Da Silva Filho, Marlon Núñez, Katherine A Glass, Tate Oulton, Fiona Achcar, Grennady Wirjanata, Manoj Duraisingh, Philip Felgner, Kevin KA Tetteh, et al.goat anti-human IgG Texas Red secondary antibody (Southern Biotech). The arrays were scanned using a GenePix 4300A scanner (Molecular Devices) at 5-µm resolution and a wavelength of 594 nm (105). Protein microarray

(2) Papain-Based Solubilization of Decellularized Extracellular Matrix for the Preparation of Bioactive, Thermosensitive PregelsBiomacromoleculesDecember 11, 2023Ahed Almalla, Laura Elomaa, Leïla Bechtella, Assal Daneshgar, Prabhu Yavvari, Zeinab Mahfouz, Peter Tang, Beate Koksch, Igor Sauer, Kevin Pagel, et al.manufacturer’s protocol without any modifications. The fluorescence signal was read at 532 nm using a GenePix 4300A microarray scanner (Molecular Devices, USA), and the concentration of the growth factors was quantified

(3) Profiling of SARS‐CoV‐2 neutralizing antibody‐associated antigenic peptides signature using proteome microarrayMedComm (2020)October 1, 2023Mingkun Wu, Jiangfeng Liu, Xinming Wang, Xiaomei Zhang, Te Liang, Lan Chen, Tingxuan Huang, Yanan Li, Chang Zheng, Yehong Yang, et al.dissembled from the tray, and dried using centrifugation for 2 min at 2000 rpm. The array was scanned with a GenePix 4300A microarray scanner (Molecular Devices) at 10 μm resolution using a laser at 532 nm with 100% power/PMT

(4) Proteomics Identifies Circulating TIMP-1 as a Prognostic Biomarker for Diffuse Large B-Cell LymphomaMolecular & Cellular ProteomicsSeptember 1, 2023Ning Lou, Guibin Wang, Yanrong Wang, Meng Xu, Yu Zhou, Qiaoyun Tan, Qiaofeng Zhong, Lei Zhang, Xiaomei Zhang, Shuxia Liu, et al.then washed three times with PBS containing 5% Tween-20. The fluorescent readout was detected using a GenePix 4300A microarray scanner at a wavelength of 532 nm (Molecular Devices). The signal intensity was extracted

(5) Clinical and humoral immune response characterization of SARS-CoV-2 Omicron BA.2.38 infection in pediatric patientsHeliyonJuly 11, 2023Yu Liu, Liunuobei Zhao, Li Wang, Yuxia Li, Longde Wang, Bo Yu, Di Hu, Heng Weng, Jianwen Guo, Jinghua Yang, et al.(Jackson Immuno Research, cat no. 109-605-043)] for 30 min. The resulting array was scanned with a GenePix 4300A microarray scanner (Molecular Devices, LLC, San Jose, CA, USA). The median fluorescent signal intensity

(6) Relevance of Host Cell Surface Glycan Structure for Cell Specificity of Influenza A VirusesVirusesJuly 5, 2023Markus Kastner, Andreas Karner, Rong Zhu, Qiang Huang, Andreas Geissner, Anne Sadewasser, Markus Lesch, Xenia Wörmann, Alexander Karlas, Peter H. Seeberger, et al.dipped into distilled water before scanning. Glycan array fluorescence images were obtained using a GenePix 4300A microarray scanner (Molecular Devices, Sunnyvale, CA, USA). Fluorescence intensities of spots were evaluated

(7) Structure of the transmembrane protein 2 (TMEM2) ectodomain and its apparent lack of hyaluronidase activityWellcome Open ResearchMay 2, 2023Muyuan Niu, Molly McGrath, Douglas Sammon, Scott Gardner, Rhodri Marc Morgan, Antonio Di Maio, Yan Liu, Doryen Bubeck, Erhard HohenesterAlexa Fluor-647-labelled streptavidin as mentioned above. The microarray images were recorded using a GenePix 4300A scanner (Molecular Devices). Results Crystal structure of sTMEM2 We expressed the soluble ectodomain

(8) Efficient Purification of Cowpea Chlorotic Mottle Virus by a Novel Peptide AptamerVirusesMarch 7, 2023Georg Tscheuschner, Marco Ponader, Christopher Raab, Prisca S. Weider, Reni Hartfiel, Jan Ole Kaufmann, Jule L. Völzke, Gaby Bosc-Bierne, Carsten Prinz, Timm Schwaar, et al.three times with acetate buffer, dried for 30 min under air, and scanned with a microarray scanner Axon GenePix 4300A (Axon Instruments, Molecular Devices, San Jose, CA, USA) at 635 nm. After this pre-scan, the chip was

(9) Immune profiling of SARS-CoV-2 epitopes in asymptomatic and symptomatic pediatric and adult patientsJournal of Translational MedicineFebruary 14, 2023Anna Lucia Tornesello, Chiara Botti, Alberto Micillo, Francesco Labonia, Sergio Arpino, Maria Antonietta Isgrò, Serena Meola, Luigi Russo, Ernesta Cavalcanti, Silvia Sale, et al.0.1 µg/ml. After washing with TBS buffer and drying, the slides were scanned with a high-resolution Genepix 4300A SL50 microarray scanner (Molecular Devices LLC, San Josè, USA) at 635 nm. The mean pixel intensity value

(10) Increased Galectin-9 Levels Correlate with Disease Activity in Patients with DMARD-Naïve Rheumatoid Arthritis and Modulate the Secretion of MCP-1 and IL-6 from Synovial FibroblastsCellsJanuary 15, 2023Nielsen MA, Køster D, Mehta AY, Stengaard-Pedersen K, Busson P, Junker P, Hørslev-Petersen K, Hetland ML, Østergaard M, Hvid M, et al.way. The binding signals were directly quantified after the incubation and slides were scanned with a GenePix 4300A microarray scanner (Molecular Devices, Sunnyvale, CA, USA), photomultiplier (PMT): 450, Laser Power

(11) The structure of a Bacteroides thetaiotaomicron carbohydrate-binding module provides new insight into the recognition of complex pectic polysaccharides by the human microbiomeJournal of Structural Biology: XJanuary 2, 2023Filipa Trovão, Viviana G. Correia, Frederico M. Lourenço, Diana O. Ribeiro, Ana Luísa Carvalho, Angelina S. Palma, Benedita A. Pinheirosolution. Binding assays were conducted at room temperature. All microarray slides were scanned with GenePix® 4300A fluorescence scanner, and the fluorescence was quantified using GenePix® Pro Software (both from Molecular Devices

(12) Novel neutralizing chicken IgY antibodies targeting 17 potent conserved peptides identified by SARS-CoV-2 proteome microarray, and future prospectsFrontiers in ImmunologyDecember 22, 2022Jin Li, Te Liang, Ailian Hei, Xiangbin Wang, Huijun Li, Xiaobo Yu, Rui Zhao, Peng Gao, Cong Fang, Ji Zhou, et al.washed, dissembled from the tray, and then dried with a vacuum pump. The array was scanned through a GenePix 4300A microarray scanner (Molecular Devices, San Jose, CA, USA). The median intensity of the fluorescent signal

(13) Podocalyxin-Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis PathwayAdvanced science (Weinheim, Baden-Wurttemberg, Germany)November 14, 2022Chen WJ, Huang WK, Pather SR, Chang WF, Sung LY, Wu HC, Liao MY, Lee CC, Wu HH, Wu CY, et al.three times with PBST and scanned at 635 nm wavelength with a microarray fluorescence chip reader (GenePix 4300A; Molecular Devices Corporation) and scanned images were analyzed with GenePix Pro‐6.0 analysis software

(14) Antibody Response to HML ‐2 May Be Protective in Amyotrophic Lateral SclerosisAnnals of NeurologyNovember 1, 2022Marta Garcia‐Montojo, Elena Rita Simula, Saeed Fathi, Cynthia McMahan, Anubrata Ghosal, James D. Berry, Merit Cudkowicz, Abdel Elkahloun, Kory Johnson, Gina Norato, et al.was removed. The microarrays were dried in a pressurized air stream from top to bottom and scanned (GenePix 4300A, Molecular Devices LLC, CA, USA). Serum samples were diluted 1 : 200 in staining buffer and 200 μL were

(15) Mapping secretome-mediated interaction between paired neuron–macrophage single cellsProceedings of the National Academy of SciencesNovember 1, 2022Jiu Deng, Yahui Ji, Fengjiao Zhu, Lina Liu, Linmei Li, Xue Bai, Huibing Li, Xianming Liu, Yong Luo, Bingcheng Lin, et al.water, and DI water sequentially, followed by rinsing and drying, and then it was scanned using the GenePix 4300A scanner (Molecular Devices). AD patient serum samples. AD patients’ serum samples were obtained from

(16) Identification and characterization of circulating immune complexes in IgA nephropathyScience AdvancesOctober 28, 2022Yasuyuki Matsumoto, Rajindra P. Aryal, Jamie Heimburg-Molinaro, Simon S. Park, Walter J. Wever, Sylvain Lehoux, Kathrin Stavenhagen, Joanna A. E. van Wijk, Irma Van Die, Arlene B. Chapman, et al.used for detection of IgM, IgG, and IgA within purified anti-Tn antibodies. Slides were analyzed on a Genepix 4300A microarray scanner (Molecular Devices). Images were analyzed with quantitation software (GenePix Pro

(17) CasPlay provides a gRNA-barcoded CRISPR-based display platform for antibody repertoire profilingCell Rep MethodsOctober 24, 2022Barber KW, Shrock E, Elledge SJ.algorithms,Software and algorithms ,, GenePix Pro 7,Molecular Devices,N/A ,, Other,Other,Other ,, GenePix 4300A microarray scanner,Molecular Devices,GENEPIX 4300

(18) N-glycosylation of Mannose receptor (CD206) regulates glycan binding by C-type lectin domainsJournal of Biological ChemistryOctober 13, 2022Kathrin Stavenhagen, Akul Y. Mehta, Lisa Laan, Chao Gao, Jamie Heimburg-Molinaro, Irma van Die, Richard D. Cummingsbinding was performed in the presence of 5 mM EDTA instead of CaCl2. The arrays were scanned using a GenePix 4300A scanner (Molecular Devices) at 488 nm, and data readout was performed using the GenePix Pro software

(19) Computationally guided conversion of the specificity of E-selectin to mimic that of Siglec-8Proceedings of the National Academy of SciencesOctober 11, 2022Xiaocong Wang, Melinda S. Hanes, Richard D. Cummings, Robert J. Woodswhich included 10 mM EDTA in the binding buffer instead of CaCl2. Microarray slides were scanned with a Genepix 4300A (Molecular Devices) and quantified with Genepix Pro-7 software. The results are shown as relative fluorescent

(20) Crystal structure of Arabidopsis DWARF14‐LIKE2 (DLK2) reveals a distinct substrate binding pocket architecturePlant DirectSeptember 13, 2022Marco Bürger, Kaori Honda, Yasumitsu Kondoh, Sharon Hong, Nobumoto Watanabe, Hiroyuki Osada, Joanne Choryconjugate, 50 μg/ml) at 30°C for 1 h. After the final wash step, slides were scanned at 635 nm on a GenePix 4300A microarray scanner (Molecular Devices). 2.6 Enzymatic analyses Enzymatic activity was measured using

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GenePix 4300A & 4400A Microarray Scanners from Molecular Devices LLC

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GenePix 4300A & 4400A Microarray Scanners from Molecular Devices LLC

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