Who would have thought that the humble nucleic acids described decades ago by Watson and Crick would one day be eyed as therapeutic or diagnostic agents world-wide? With customized modifications, today’s oligonucleotides are doing more than probing blots in the lab. And in many cases, buying is cheaper than...
RNAi technology has advanced far beyond the speculative phase, and researchers are looking for higher quality siRNA in greater quantities and wider gene coverage than ever before. Much of the spike in demand comes from RNA interference drug screens for drug target identification or validation. Large scale screens often follow...
Real-time quantitative PCR has undoubtedly hit its stride as the go-to protocol for assessing gene expression. Emerging about 10 years ago, this gene-quantifying technology introduced vast improvements over its...
Integrated DNA Technologies (IDT) synthesizes custom DNA and RNA sequences to order. As a molecular biologist, I buy a lot of primers. Most of my purchases from IDT have been pretty straightforward sequences: short oligonucleotide primers for...